Research information only. Not medical advice. 18+ only. Not FDA-approved for human therapeutic use.

Follistatin 315 vs Follistatin-344

Comparison

Follistatin 315 and Follistatin-344 are two peptides people frequently compare. Researchers study Follistatin-315 for its role in muscle growth, liver regeneration, and bone repair by blocking the body's natural muscle-limiting signals. It's investigated as a potential therapy… Follistatin-344 is a peptide people use for muscle building, primarily because it inhibits myostatin — the body's natural brake on muscle growth. It's studied for muscle wasting diseases and has been…

Follistatin 315 Follistatin-344
What it is Researchers study Follistatin-315 for its role in muscle growth, liver regeneration, and bone repair by blocking the body's natural muscle-limiting signals. It's investigated as a potential therapy… Follistatin-344 is a peptide people use for muscle building, primarily because it inhibits myostatin — the body's natural brake on muscle growth. It's studied for muscle wasting diseases and has been…
Primary uses
  • Muscle hypertrophy / muscle wasting diseases
  • Liver regeneration
  • Regulation of hepcidin / anemia of inflammation
  • Bone repair / tissue engineering
  • Skeletal muscle mass enhancement / myostatin inhibition
  • Sports/athletic performance enhancement (unapproved, 'gray market' use)
  • Biomarker of physical functional impairment in rheumatoid arthritis
  • FSH suppression / reproductive endocrinology (endogenous role)
How it works It's investigated as a potential therapy for muscle wasting diseases. No FDA-approved therapeutic use; prohibited by WADA; evidence comes primarily from animal models and lab studies. It's studied for muscle wasting diseases and has been used off-label by athletes seeking physique enhancement. No FDA-approved use; prohibited by WADA; most evidence from animal models.
Common dose 100 mcg, intramuscular, once daily 100 mcg, intramuscular (IM) injection, once daily
FDA status Not stated in reviewed literature — requires manual verification. No approved pharmaceutical formulations noted in reviewed literature. Not stated in reviewed literature — requires manual verification. No approved pharmaceutical formulations of follistatin noted in reviewed literature.
Evidence level Mixed Human observational