Human Chorionic Gonadotropin (hCG) vs Gonadorelin
Comparison
Human Chorionic Gonadotropin (hCG) and Gonadorelin are two peptides people frequently compare. Human Chorionic Gonadotropin (hCG) is a hormone used in fertility treatment to trigger ovulation and support early pregnancy. It works by mimicking LH, the hormone that tells the ovaries to release… Gonadorelin is the synthetic form of the natural hormone that triggers the pituitary to release sex hormones; it's used in fertility treatment and diagnostic testing. It works by pulsing the…
| Human Chorionic Gonadotropin (hCG) | Gonadorelin | |
|---|---|---|
| What it is | Human Chorionic Gonadotropin (hCG) is a hormone used in fertility treatment to trigger ovulation and support early pregnancy. It works by mimicking LH, the hormone that tells the ovaries to release… | Gonadorelin is the synthetic form of the natural hormone that triggers the pituitary to release sex hormones; it's used in fertility treatment and diagnostic testing. It works by pulsing the… |
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| How it works | It works by mimicking LH, the hormone that tells the ovaries to release an egg and maintain progesterone levels. Approved for fertility use in many countries; banned by WADA in male athletes. | it's used in fertility treatment and diagnostic testing. It works by pulsing the pituitary to stimulate the hormones that drive testosterone and estrogen production. Not FDA-approved as a standalone… |
| Common dose | 500 IU, subcutaneous injection, every other day (EOD) | 100 mcg, subcutaneous injection, twice weekly (e.g. Monday and Thursday) |
| FDA status | Not stated in reviewed literature — requires manual verification. Note: PMID 19817556 states that the US FDA considers only regular (intact heterodimeric) hCG as part of a pregnancy test for… | Not stated in reviewed literature — requires manual verification |
| Evidence level | Human RCT | Human RCT |
| Full Human Chorionic Gonadotropin (hCG) page → | Full Gonadorelin page → |