Research information only. Not medical advice. 18+ only. Not FDA-approved for human therapeutic use.

Ipamorelin vs CJC-1295

Comparison

Ipamorelin and CJC-1295 are two peptides people frequently compare. Ipamorelin is a peptide people use to boost their body's own growth hormone output. It's taken for muscle recovery, body composition, better sleep, and recovery after illness or surgery. Not… CJC-1295 is a peptide people use to raise their growth hormone levels for muscle building, fat loss, and recovery. It works by extending the action of a natural hormone that tells the pituitary to…

Ipamorelin CJC-1295
What it is Ipamorelin is a peptide people use to boost their body's own growth hormone output. It's taken for muscle recovery, body composition, better sleep, and recovery after illness or surgery. Not… CJC-1295 is a peptide people use to raise their growth hormone levels for muscle building, fat loss, and recovery. It works by extending the action of a natural hormone that tells the pituitary to…
Primary uses
  • Growth hormone stimulation / GH-IGF-1 axis modulation
  • Postoperative ileus / gastrointestinal motility
  • Counteracting glucocorticoid-induced muscle and bone catabolism
  • Bone mineral content and longitudinal bone growth
  • Stimulation of GH and IGF-1 secretion in healthy adults (pharmacokinetic/pharmacodynamic characterisation)
  • Identification of GH/IGF-1-related serum protein biomarkers
  • Normalisation of growth in GHRH-deficient (knockout) mice
  • Rescue of growth deficit in brain-specific M3 muscarinic receptor knockout mice
How it works It's taken for muscle recovery, body composition, better sleep, and recovery after illness or surgery. Not FDA-approved; classified as investigational. It works by extending the action of a natural hormone that tells the pituitary to release growth hormone. Not FDA-approved; banned by WADA; classified as a prohibited performance-enhancing substance.
Common dose 200 mcg, subcutaneous injection, once daily, pre-sleep 1000 mcg, subcutaneous injection, once weekly
FDA status Not stated in reviewed literature as FDA-approved for any indication. Reviewed literature describes ipamorelin as an unapproved/investigational compound for performance and musculoskeletal… Not approved by the FDA for any indication. Classified as a prohibited performance-enhancing substance by WADA. (PMID: 41966639, 41880199, 31849 — see WADA status below)
Evidence level Human RCT Human RCT